{"id":2487,"date":"2012-09-09T19:10:42","date_gmt":"2012-09-09T11:10:42","guid":{"rendered":"http:\/\/vanabel.sinaapp.com\/?p=2487"},"modified":"2012-09-09T19:10:42","modified_gmt":"2012-09-09T11:10:42","slug":"%e8%bd%ac%e8%bd%bd%e5%9e%83%e5%9c%bedna%e4%b8%8d%e5%9e%83%e5%9c%be","status":"publish","type":"post","link":"https:\/\/lttt.vanabel.cn\/?p=2487","title":{"rendered":"[\u8f6c\u8f7d]\u201c\u5783\u573eDNA\u201d\u4e0d\u5783\u573e"},"content":{"rendered":"<p><a title=\"\u201c\u5783\u573eDNA\u201d\u4e0d\u5783\u573e\" href=\"http:\/\/www.guokr.com\/article\/331400\/\" target=\"_blank\">\u539f\u6587\u94fe\u63a5<\/a><\/p>\n<hr \/>\n<p><span style=\"color: #666; font-style: italic;\">\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u7684\u540e\u7eed\u3001DNA\u5143\u4ef6\u767e\u79d1\u5168\u4e66\uff08ENCODE\uff09\u6570\u636e\u5e93\u8ba1\u5212\u5386\u65f69\u5e74\u7ec8\u6210\uff0c\u8fd9\u4e5f\u8bb8\u662f\u672c\u4e16\u7eaa\u8fc4\u4eca\u6700\u91cd\u5927\u7684\u751f\u7269\u5b66\u548c\u533b\u5b66\u6210\u679c\u3002\u5176\u4e2d\u6700\u91cd\u5927\u7684\u53d1\u73b0\u662f\uff1a\u5783\u573e DNA \u4e0d\u5783\u573e\u3002\u8be5\u7814\u7a76\u6709\u671b\u6539\u5199\u6211\u4eec\u7406\u89e3\u4eba\u7c7b\u57fa\u56e0\u7ec4\u3001\u6cbb\u7597\u9057\u4f20\u76f8\u5173\u75be\u75c5\u7684\u65b9\u5f0f\u3002<\/span><br \/>\n<!--more--><\/p>\n<hr \/>\n<p>\u5386\u65f6 9 \u5e74\uff0c\u5728\u5168\u4e16\u754c 32 \u4e2a\u5b9e\u9a8c\u5ba4\u7684 442 \u540d\u7814\u7a76\u4eba\u5458\u7684\u52aa\u529b\u4e0b\uff0c\u201cDNA \u5143\u4ef6\u767e\u79d1\u5168\u4e66\u201d\u6570\u636e\u5e93\u8ba1\u5212\uff08\u00a0<a href=\"http:\/\/genome.ucsc.edu\/ENCODE\/\" target=\"_blank\">Encyclopedia of DNA Elements<\/a>\u00a0\uff0cENCODE\uff09\u7ec8\u4e8e\u7528 30 \u7bc7\u8bba\u6587\u53d1\u8868\u4e86\u00a0<a href=\"http:\/\/www.nature.com\/encode\/#\/threads\" target=\"_blank\">\u4ed6\u4eec\u7684\u7ed3\u679c<\/a>\u00a0\uff0c\u8fd9\u4e5f\u8bb8\u662f\u672c\u4e16\u7eaa\u8fc4\u4eca\u4e3a\u6b62\u6700\u91cd\u5927\u7684\u751f\u7269\u5b66\u548c\u533b\u5b66\u6210\u679c\u3002\u5176\u4e2d\uff0c\u6700\u4e3a\u6838\u5fc3\u7684\u53d1\u73b0\u662f\uff1a\u5783\u573e DNA \u4e0d\u5783\u573e\u3002\u8be5\u7814\u7a76\u6709\u671b\u6539\u5199\u6211\u4eec\u7406\u89e3\u4eba\u7c7b\u57fa\u56e0\u7ec4\u3001\u6cbb\u7597\u9057\u4f20\u76f8\u5173\u75be\u75c5\u7684\u65b9\u5f0f\u3002\u5982\u679c\u8bf4\u5728\u6b64\u4e4b\u524d\u7684\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u53ea\u662f\u4e00\u5f20\u822a\u62cd\u7167\u7247\uff0c\u90a3\u4e48\u6b64\u9879\u7814\u7a76\u5219\u5448\u73b0\u51fa\u4e86\u57fa\u56e0\u7ec4\u7684 Google \u5730\u56fe\u3002<\/p>\n<p>\u8fc7\u53bb\u4eba\u4eec\u8ba4\u4e3a\uff0c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e2d 90% \u4ee5\u4e0a\u7684\u5e8f\u5217\u662f\u6ca1\u6709\u4efb\u4f55\u4f5c\u7528\u7684\u201c\u5783\u573eDNA\u201d\uff0c\u4f46 ENCODE \u7684\u7ed3\u679c\u663e\u793a\uff0c\u4eba\u7c7b\u57fa\u56e0\u7ec4 80% \u7684\u6210\u5206\u6709\u81f3\u5c11\u4e00\u79cd\u751f\u5316\u529f\u80fd\u3002\u5f88\u591a\u8fc7\u53bb\u88ab\u8ba4\u4e3a\u5e76\u975e\u57fa\u56e0\u7684\u6210\u5206\uff0c\u5b9e\u9645\u4e0a\u6216\u8005\u53ef\u4ee5\u8f6c\u5f55\u4e3a RNA\uff0c\u6216\u8005\u4f5c\u4e3a\u8f6c\u5f55\u56e0\u5b50\u7ed3\u5408\u4f4d\u70b9\uff0c\u6216\u8005\u662f DNA \u5316\u5b66\u4fee\u9970\u7684\u9776\u70b9\uff0c\u4ee5\u591a\u79cd\u5f62\u5f0f\u5bf9\u771f\u6b63\u57fa\u56e0\u7684\u8868\u8fbe\u8d77\u5230\u4e86\u5173\u952e\u7684\u8c03\u8282\u4f5c\u7528\u3002\u57fa\u56e0\u548c\u975e\u57fa\u56e0\u7684\u754c\u9650\u6b63\u5728\u9010\u6e10\u6a21\u7cca\u3002<\/p>\n<p>ENCODE \u8fd8\u8ba9\u4eba\u4eec\u91cd\u65b0\u8ba4\u8bc6\u4e86 RNA \u7684\u4f5c\u7528\u3002\u8fc7\u53bb\u66fe\u7ecf\u8ba4\u4e3a RNA \u4e3b\u8981\u4f5c\u7528\u53ea\u662f\u86cb\u767d\u8d28\u5408\u6210\u7684\u4e2d\u95f4\u4ea7\u7269\uff0c\u4f46 ENCODE \u53d1\u73b0\u5927\u90e8\u5206 RNA \u672c\u8eab\u5c31\u662f\u7ec8\u4ea7\u7269\uff0c\u6709\u91cd\u8981\u751f\u7406\u529f\u80fd\uff0c\u4e0d\u4f1a\u518d\u7ffb\u8bd1\u6210\u86cb\u767d\u8d28\u3002<\/p>\n<p>\u6b64\u5916\uff0cENCODE \u5bf9\u8868\u89c2\u9057\u4f20\u5b66\u3001\u57fa\u56e0\u76f8\u4e92\u4f5c\u7528\u3001\u9057\u4f20\u53d8\u5f02\u7684\u7279\u5f81\u4ee5\u53ca\u4eba\u7c7b\u6f14\u5316\u8fc7\u7a0b\u7b49\u7b49\u9886\u57df\u90fd\u4f1a\u4ea7\u751f\u91cd\u5927\u5f71\u54cd\uff0c\u5bf9\u4e8e\u7406\u89e3\u548c\u6cbb\u6108\u4f17\u591a\u9057\u4f20\u76f8\u5173\u7684\u4eba\u7c7b\u75be\u75c5\u66f4\u662f\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>MIT \u548c\u54c8\u4f5b\u8054\u5408\u8bbe\u7acb\u7684\u535a\u5fb7\u7814\u7a76\u6240\u4e3b\u5e2d\u00a0<a href=\"http:\/\/www.guokr.com\/article\/84994\/\" target=\"_blank\">\u57c3\u91cc\u514b\u00b7\u5170\u5fb7<\/a>\u00a0\uff08Eric Lander\uff09\u5c06\u4e4b\u6bd4\u55bb\u6210 \u201c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7684 Google \u5730\u56fe\u201d\u3002\u4ed6\u8bf4\uff0c\u4e4b\u524d\u7684\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u5982\u540c\u536b\u661f\u7167\u7247\uff0c\u4e0d\u80fd\u544a\u8bc9\u4f60\u54ea\u91cc\u662f\u9053\u8def\uff0c\u54ea\u6761\u8def\u4e00\u5929\u5185\u7684\u4ea4\u901a\u60c5\u51b5\u53d8\u5316\u5982\u4f55\uff0c\u54ea\u91cc\u662f\u57ce\u5e02\uff0c\u54ea\u91cc\u662f\u533b\u9662\uff0c\u54ea\u91cc\u6709\u597d\u9910\u9986\u3002\u800c ENCODE \u8ba1\u5212\u5219\u80fd\u591f\u5c06\u8fd9\u4e00\u5207\u90fd\u6807\u6ce8\u5728\u4eba\u7c7b\u7684\u57fa\u56e0\u7ec4\u4e0a\u3002<\/p>\n<p>\u8fd9\u4e9b\u7814\u7a76\u4ee5 6 \u7bc7\u300a\u81ea\u7136\u300b\u8bba\u6587\u300118 \u7bc7\u300a\u57fa\u56e0\u7ec4\u7814\u7a76\u300b\uff08Genome Research\uff09\u8bba\u6587\u548c 6 \u7bc7\u300a\u57fa\u56e0\u7ec4\u751f\u7269\u5b66\u300b\uff08Genome Biology\uff09\u8bba\u6587\u7684\u5f62\u5f0f\u9762\u4e16\u3002\u300a\u79d1\u5b66\u300b\u4e5f\u5728\u7ebf\u53d1\u8868\u4e86\u4e24\u7bc7\u6587\u7ae0\u3002\u300a\u751f\u7269\u5316\u5b66\u6742\u5fd7\u300b\uff08The Journal of Biological Chemistry\uff09\u8fd8\u6709 6 \u7bc7\u8bc4\u8bba\u6587\u7ae0\u5f85\u53d1\u3002\u8ba1\u5212\u7684\u9886\u5bfc\u8005\u4e4b\u4e00\u9a6c\u514b\u00b7\u683c\u65af\u5766\uff08Mark B. Gerstein\uff09\u535a\u58eb\u8bf4\uff0c\u8fd9\u7b80\u76f4\u662f\u201c\u4e00\u652f\u8bba\u6587\u8230\u961f\u201d\u3002<\/p>\n<div id=\"dna-dna\">\n<h1>\u201c\u5783\u573eDNA\u201d\u4e0d\u5783\u573e\u2014\u2014\u91cd\u65b0\u8ba4\u77e5\u5783\u573e DNA<\/h1>\n<div>\n<p><img decoding=\"async\" src=\"http:\/\/i.imgur.com\/lR3gM.png\" alt=\"\u4e00\u5927\u7fa4\u79d1\u5b66\u5bb6\u901a\u8fc7\u7814\u7a76\u53d1\u73b0\uff0c\u5360\u636e\u4e86\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e00\u5927\u5757\u7684\u6240\u8c13\u7684\u201c\u5783\u573eDNA\u201d\uff0c\u8fdc\u6bd4\u6211\u4eec\u4e4b\u524d\u60f3\u5f97\u8981\u6709\u7528\u3002\uff08\u56fe\u7247\uff1aEncode\uff0cvia The New York Times\uff09\" \/><\/p>\n<p>\u4e00\u5927\u7fa4\u79d1\u5b66\u5bb6\u901a\u8fc7\u7814\u7a76\u53d1\u73b0\uff0c\u5360\u636e\u4e86\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e00\u5927\u5757\u7684\u6240\u8c13\u7684\u201c\u5783\u573eDNA\u201d\uff0c\u8fdc\u6bd4\u6211\u4eec\u4e4b\u524d\u60f3\u5f97\u8981\u6709\u7528\u3002\uff08\u56fe\u7247\uff1aEncode\uff0cvia The New York Times\uff09<\/p>\n<\/div>\n<ul>\n<li><strong>\u57fa\u56e0<\/strong>\u00a0\u6bcf\u4e00\u4e2a\u4eba\u7c7b\u7ec6\u80de\u90fd\u5305\u542b\u7740\u5377\u6210\u7d27\u5bc6\u5c0f\u56e2\u7684 DNA\uff0c\u5728\u62c9\u5f00\u4e4b\u540e\u80fd\u8fbe\u5230 10 \u82f1\u5c3a\u957f\uff08\u5927\u7ea6 3\u7c73\uff09\u3002\u4f46\u5176\u4e2d\u53ea\u6709\u5f88\u5c11\u4e00\u90e8\u5206\u4f1a\u7f16\u7801\u57fa\u56e0\uff0c\u6765\u63a7\u5236\u773c\u775b\u989c\u8272\u3001\u8840\u578b\u7b49\u7b49\u9057\u4f20\u6027\u72b6\u3002<\/li>\n<li><strong>\u5783\u573eDNA<\/strong>\u00a0\u5728\u57fa\u56e0\u5468\u56f4\u3001\u57fa\u56e0\u4e4b\u95f4\uff0c\u6709\u5f88\u591a\u770b\u8d77\u6765\u5565\u4e5f\u4e0d\u505a\u7684 DNA\uff0c\u5b83\u4eec\u88ab\u79f0\u4f5c \u201c\u5783\u573eDNA\u201d\u3002\u4f46\u73b0\u5728\uff0c\u7814\u7a76\u8005\u8ba4\u4e3a\u5783\u573e DNA \u4e2d\u542b\u6709\u5927\u91cf\u5fae\u5c0f\u7684\u57fa\u56e0\u5f00\u5173\uff0c\u63a7\u5236\u7740\u57fa\u56e0\u5728\u7ec6\u80de\u4e2d\u7684\u529f\u80fd\u3002<\/li>\n<li><strong>\u8c03\u63a7<\/strong>\u00a0\u8bb8\u591a\u57fa\u56e0\u8c03\u63a7\u5b50\u4f3c\u4e4e\u90fd\u5904\u4e8e\u4e00\u4e2a\u590d\u6742\u800c\u5197\u4f59\u7684\u5c42\u7ea7\u7ed3\u6784\u5f53\u4e2d\u3002\u8fd9\u4e2a\u7f51\u7edc\u8c03\u63a7\u7740\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u5668\u5b98\u7684\u6d3b\u52a8\uff0c\u800c\u79d1\u5b66\u5bb6\u73b0\u5728\u624d\u521a\u521a\u5f00\u59cb\u5bf9\u5b83\u8fdb\u884c\u63cf\u7ed8\u548c\u7406\u89e3\u3002<\/li>\n<li><strong>\u75be\u75c5<\/strong>\u00a0\u57fa\u56e0\u5f00\u5173\u7684\u51fa\u9519\u6216\u7a81\u53d8\u53ef\u4ee5\u6270\u4e71\u8fd9\u4e2a\u7f51\u7edc\uff0c\u5bfc\u81f4\u4e00\u7cfb\u5217\u75be\u75c5\u3002\u8fd9\u4e9b\u65b0\u53d1\u73b0\u4f1a\u6fc0\u52b1\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\uff0c\u50ac\u751f\u65b0\u7684\u836f\u7269\u4ee5\u53ca\u6cbb\u7597\u65b9\u5f0f\u7684\u51fa\u73b0\u3002<\/li>\n<\/ul>\n<table frame=\"void\" rules=\"none\">\n<colgroup>\n<col \/>\n<col \/><\/colgroup>\n<tbody valign=\"top\">\n<tr>\n<th>\u7f16\u8bd1\u81ea:<\/th>\n<td>\n<div>\n<div>Science\uff0cHuman Genome Is Much More Than Just Genes<\/div>\n<div>The New York Times\uff0cBits of Mystery DNA, Far From \u2018Junk,\u2019 Play Crucial Role<\/div>\n<div>Nature\uff0cPresenting ENCODE<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<tr>\n<th>\u6587\u7ae0\u9898\u56fe:<\/th>\n<td>VLADGRIN\/SHUTTERSTOCK\uff0cvia nature.com<\/td>\n<\/tr>\n<tr>\n<th>\u5185\u6587\u56fe\u7247:<\/th>\n<td>The New York Times\uff0cRethinking \u2018Junk\u2019 DNA<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u539f\u6587\u94fe\u63a5 \u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u7684\u540e\u7eed\u3001DNA\u5143\u4ef6\u767e\u79d1\u5168\u4e66\uff08ENCODE\uff09\u6570\u636e\u5e93\u8ba1\u5212\u5386\u65f6 &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"more-link\" href=\"https:\/\/lttt.vanabel.cn\/?p=2487\"> <span class=\"screen-reader-text\">[\u8f6c\u8f7d]\u201c\u5783\u573eDNA\u201d\u4e0d\u5783\u573e<\/span> \u9605\u8bfb\u66f4\u591a &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[362,368,148],"class_list":["post-2487","post","type-post","status-publish","format-standard","hentry","category-net","tag-dna","tag-encode","tag-148"],"_links":{"self":[{"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=\/wp\/v2\/posts\/2487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2487"}],"version-history":[{"count":0,"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=\/wp\/v2\/posts\/2487\/revisions"}],"wp:attachment":[{"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2487"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2487"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lttt.vanabel.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}